Vol. 87

Front:[PDF file] Back:[PDF file]
Latest Volume
All Volumes
All Issues
2019-09-18

Simulation Study on Forward Problem of Magnetoacoustic Tomography with Magnetic Induction Based on Magnetic Nanoparticles

By Xiaoheng Yan, Ye Pan, Ying Zhang, and Sichen Guang
Progress In Electromagnetics Research Letters, Vol. 87, 75-80, 2019
doi:10.2528/PIERL19060309

Abstract

Magnetoacoustic tomography with magnetic induction (MAT-MI) is a multiphysics imaging technique that combines electrical impedance imaging with ultrasound imaging. In order to study the influence of parameters on the source of MAT-MI , such as radius and permeability of magnetic nanoparticle clusters, the paper is divided into the following stages. Firstly, this paper analyzes the electromagnetic and acoustic properties of MAT-MI after adding magnetic nanoparticles. Secondly, to determine the suitable simulation conditions, a two-dimensional model is constructed. Thirdly, use the finite element method to solve physical processes of electromagnetic field and acoustic field under conditions of different magnetic nanoparticle clusters' radii and permeabilities, then obtain the magnetic flux density image. Consequently, make the qualitative and quantitative analysis according to the theory and simulation results. The results show that magnetic nanoparticle clusters interact with each other and distort the magnetic field to different degrees; its radius increases with the degree of flux density distortion around it, so does its permeability and magnetoacoustic signal intensity. The research results can play a guiding role in the parameter selection of magnetic nanoparticle clusters in practical applications to a certain extent.

Citation


Xiaoheng Yan, Ye Pan, Ying Zhang, and Sichen Guang, "Simulation Study on Forward Problem of Magnetoacoustic Tomography with Magnetic Induction Based on Magnetic Nanoparticles," Progress In Electromagnetics Research Letters, Vol. 87, 75-80, 2019.
doi:10.2528/PIERL19060309
http://www.jpier.org/PIERL/pier.php?paper=19060309

References


    1. Zhu, J., et al., "Progress of electromagnetic detection and imaging of magnetic nanoparticles," Chinese Journal of Biomedical Engineering, Vol. 37, No. 3, 344-352, 2018.

    2. Lu, S., "Research progress of magnetic nanoparticles," Popular Science & Technology, Vol. 19, No. 3, 38-39, 2017.

    3. Pankhurst, Q. A., et al., "Applications of magnetic nanoparticles in biomedicine," Journal of Physics D: Applied Physics, Vol. 36, No. 13, R167, 2003.
    doi:10.1088/0022-3727/36/13/201

    4. Kalambur, V. S., et al., "In vitro characterization of movement, heating and visualization of magnetic nanoparticles for biomedical applications," Nanotechnology, Vol. 16, No. 8, 1221, 2005.
    doi:10.1088/0957-4484/16/8/041

    5. Ito, A., et al., "Magnetite nanoparticle-loaded anti-HER2 immunoliposomes for combination of antibody therapy with hyperthermia," Cancer Letters, Vol. 212, No. 2, 167-175, 2004.
    doi:10.1016/j.canlet.2004.03.038

    6. Steinberg, I., M. Ben-David, and I. Gannot, "A new method for tumor detection using induced acoustic waves from tagged magnetic nanoparticles," Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 8, No. 5, 569-79, 2012.
    doi:10.1016/j.nano.2011.09.011

    7. Norton, S. J. and T. Vo-Dinh, "Imaging the distribution of magnetic nanoparticles with ultrasound," IEEE Transactions on Medical Imaging, Vol. 26, No. 5, 660-5, 2007.
    doi:10.1109/TMI.2007.895476

    8. Tsalach, A., I. Steinberg, and I. Gannot, "Tumor localization using magnetic nanoparticle-induced acoustic signals," IEEE Transactions on Biomedical Engineering, Vol. 61, No. 8, 2313-2323, 2014.
    doi:10.1109/TBME.2013.2286638

    9. Oh, J., et al., "Detection of magnetic nanoparticles in tissue using magnetomotive ultrasound," Nanotechnology, Vol. 17, No. 16, 167-175, 2006.
    doi:10.1088/0957-4484/17/16/031

    10. Xu, Y. and B. He, "Magnetoacoustic tomography with magnetic induction (MAT-MI)," Physics in Medicine & Biology, Vol. 50, No. 21, 5175, 2005.
    doi:10.1088/0031-9155/50/21/015

    11. Hu, G. and B. He, "Magnetoacoustic imaging of magnetic iron oxide nanoparticles embedded in biological tissues with microsecond magnetic stimulation," Applied Physics Letters, Vol. 100, No. 1, 013704, 2012.
    doi:10.1063/1.3675457

    12. Mariappan, L., et al., "Magneto acoustic tomography with short pulsed magnetic field for in-vivo imaging of magnetic iron oxide nanoparticles," Nanomedicine- Nanotechnology Biology and Medicine, Vol. 12, No. 3, 689-699, 2016.
    doi:10.1016/j.nano.2015.10.014

    13. Yan, X. H., Y. Zhang, and G. Q. Liu, "Simulation research on effect of magnetic nanoparticles on physical process of magneto-acoustic tomography with magnetic induction," Chinese Physics B, Vol. 27, No. 10, 2018.
    doi:10.1088/1674-1056/27/10/104302

    14. Pothayee, N., et al., "Synthesis of ‘ready-to-adsorb’ polymeric nanoshells for magnetic iron oxide nanoparticles via atom transfer radical polymerization," Polymer, Vol. 52, No. 6, 1356-1366, 2011.
    doi:10.1016/j.polymer.2011.01.047

    15. Xu, H., et al., "Characterization of individual magnetic nanoparticles in solution by double nanohole optical tweezers," Nano Letters, Vol. 16, No. 4, 2639-2643, 2016.
    doi:10.1021/acs.nanolett.6b00288