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PIER PIER B PIER C PIER M PIER Letters PIER Photonics
2012-07-25
Design and Optimization of High Sensitivity Photonic Interferometric Biosensors on Polymeric Waveguides
By
Giovanna Calo,

    Dr. Giovanna Calo

    Dipartimento di elettrotecnica ed elettronica

    Politecnico di Bari

    Italy

    Homepage

Antonio Farinola,

    Dr. Antonio Farinola

    Dipartimento di Elettrotecnica ed Elettronica

    Politecnico di Bari

    Italy

    Homepage

Vincenzo Petruzzelli

    Professor Vincenzo Petruzzelli

    Dipartimento di Elettrotecnica ed Elettronica

    Politecnico di Bari

    Italy

    Homepage

Progress In Electromagnetics Research Letters, Vol. 33, 151-166, 2012
doi:10.2528/PIERL12051303 | Google Scholar

Abstract
The design criteria of integrated optical biosensors based on the Mach-Zehnder Interferometer and on the Michelson Interferometer are proposed. Sensitive performance has been evaluated for different optical polymeric waveguiding structures such as channel, inverted-rib and strip waveguides. For all the configurations of the examined optical waveguiding interferometric biosensors maximum linearity and sensitivity have been obtained. In particular, the achieved sensitivity, expressed as the ratio between the normalized output power and the protein concentration, is about equal to 1.6 (g/ml)-1 which, for a maximum variation of the output power equal to 100 mW, leads to a non-normalized sensitivity equal to 160 mW/(g/ml).
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Citation
Giovanna Calo, Antonio Farinola, and Vincenzo Petruzzelli, "Design and Optimization of High Sensitivity Photonic Interferometric Biosensors on Polymeric Waveguides," Progress In Electromagnetics Research Letters, Vol. 33, 151-166, 2012.
doi:10.2528/PIERL12051303
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