volume | PIER Journals

Abstract

This paper investigates the direct detection of glucose in the visible light spectrum using a spectroscopy method. The method, which detects glucose without the need for additional enzymes or reagents, is developed using a light-emitting diode, a photodetector, and a data acquisition card (DAQ) to form a simple spectroscopy system. The system, operating at wavelengths of 505 nm, 700 nm, and 840 nm, has been experimentally tested for performance characterization. The experimental results show that the 505 nm operating wavelength produces optimal performance, with a linearity range of 20-45 mg/dL, a linearity value of 0.8812, sensitivity of 1.1 mV(mg/dL)^-1, stability precision greater than 99%, and a limit of detection (LOD) of 12.72 mg/dL. At this wavelength, the developed system improves sensitivity performance by about 69% compared to previous reports. This enhancement provides an alternative operating wavelength for glucose detection with better sensitivity performance.

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Dr. Afiqah Yaacob

Dr. Nor Hafizah Ngajikin

Dr. Nurfatihah Che Abd Rashid

Dr. Siti Hajar Aminah Ali

Dr. Maslina Yaacob

Dr. Ian Yulianti

Dr. Noran Azizan Cholan