volume | PIER Journals

Abstract

The paper presents a microwave system operating at 4-5 GHz for brain tumor diagnosis. The proposed work presents a novel method to detect the presence of tumors by capitalizing on the variations in antenna response. To achieve highly precise and fast diagnosis, a high-gain antenna is placed on the surface of the skull. The gain and directivity of the antenna are enhanced by using a Frequency selective surface (FSS) array structure placed behind the antenna which directs the energy towards the human tissues for tumor detection purposes. By using the FSS array surface, there is a 4.3 dB increase in gain and a 4.2 dB increase in directivity. Simulations are carried out using a multi-layer skull model comprising Skin, Skull, and Brain. Our proposed work demonstrates that there is a variation of about 8 dB in S-parameters when a tumor of size 6 mm × 6 mm is placed in the brain area. Further, we have investigated the S-parameter characteristics using different shapes and sizes of tumors in the brain. The results show that variation in S-parameter characteristics can potentially be used to detect the presence of tumors in the human brain.

1. Tariq, Mashal, Ayesha A. Siddiqi, Ghous B. Narejo, and Shehla Andleeb, "A cross sectional study of tumors using bio-medical imaging modalities," Current Medical Imaging, Vol. 15, No. 1, 66-73, 2019.

2. Singh, Daljeet, Erkki Vihriälä, Mariella Särestöniemi, and Teemu Myllylä, "Microwave technique based noninvasive monitoring of intracranial pressure using realistic phantom models," Nordic Conference on Digital Health and Wireless Solutions, 413-425, 2024.

3. Alqadami, Abdulrahman S. M., Konstanty S. Bialkowski, Ahmed Toaha Mobashsher, and Amin M. Abbosh, "Wearable electromagnetic head imaging system using flexible wideband antenna array based on polymer technology for brain stroke diagnosis," IEEE Transactions on Biomedical Circuits and Systems, Vol. 13, No. 1, 124-134, 2018.

4. Särestöniemi, Mariella, Daljeet Singh, Charline Heredia, Juha Nikkinen, Mikael von und zu Fraunberg, and Teemu Myllylä, "Digital twins for development of microwave-based brain tumor detection," Nordic Conference on Digital Health and Wireless Solutions, 240-254, 2024.

5. Winter, Arthur, Joy Laing, Robert Paglione, and Fred Sterzer, "Microwave hyperthermia for brain tumors," Neurosurgery, Vol. 17, No. 3, 387-399, 1985.

6. Redr, Jan, Tomas Pokorny, Tomas Drizdal, Ondrej Fiser, Matous Brunat, Jan Vrba, and David Vrba, "Microwave hyperthermia of brain tumors: A 2D assessment parametric numerical study," Sensors, Vol. 22, No. 16, 6115, 2022.

7. Dewhirst, M. W., B. L. Viglianti, M. Lora-Michiels, M. Hanson, and P. J. Hoopes, "Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia," International Journal of Hyperthermia, Vol. 19, No. 3, 267-294, 2003.

8. Lyons, Bernard E., Richard H. Britt, and John W. Strohbehn, "Localized hyperthermia in the treatment of malignant brain tumors using an interstitial microwave antenna array," IEEE Transactions on Biomedical Engineering, Vol. BME-31, No. 1, 53-62, 1984.

9. Särestöniemi, Mariella, Daljeet Singh, Jarmo Reponen, and Teemu Myllylä, "Tailored 3D breast models for development of microwave based breast tumor screening," Finnish Journal of eHealth and eWelfare, Vol. 16, No. 1, 23-34, 2024.

10. Benny, Ria, Thathamkulam A. Anjit, and Palayyan Mythili, "An overview of microwave imaging for breast tumor detection," Progress In Electromagnetics Research B, Vol. 87, 61-91, 2020.

11. Muhammad, Siti Nuranis, Muammar Mohamad Isa, and Faizal Jamlos, "Review article of microwave imaging techniques and dielectric properties for lung tumor detection," AIP Conference Proceedings, Vol. 2203, No. 1, 2020.

12. Selvaraj, Vanaja, John Bosco Joselin Jeya Sheela, Rahul Krishnan, Lalitha Kandasamy, and Sasirekha Devarajulu, "Detection of depth of the tumor in microwave imaging using ground penetrating radar algorithm," Progress In Electromagnetics Research M, Vol. 96, 191-202, 2020.

13. Gong, Zheng, Yifan Chen, Xiaoyou Lin, and Michael J. Cree, "Contrast-enhanced microwave cancer detection using angle-of-arrival approach," IEEE Transactions on Antennas and Propagation, Vol. 70, No. 5, 3772-3780, 2021.

14. Rodriguez-Duarte, David O., Jorge A. Tobon Vasquez, Rosa Scapaticci, Lorenzo Crocco, and Francesca Vipiana, "Brick-shaped antenna module for microwave brain imaging systems," IEEE Antennas and Wireless Propagation Letters, Vol. 19, No. 12, 2057-2061, 2020.

15. Hossain, Amran, Mohammad Tariqul Islam, Gan Kok Beng, Saad Bin Abul Kashem, Mohamed S. Soliman, Norbahiah Misran, and Muhammad E. H. Chowdhury, "Microwave brain imaging system to detect brain tumor using metamaterial loaded stacked antenna array," Scientific Reports, Vol. 12, No. 1, 16478, 2022.

16. Hamza, Musa N., Mohammad Tariqul Islam, and Slawomir Koziel, "Advanced sensor for non-invasive breast cancer and brain cancer diagnosis using antenna array with metamaterial-based AMC," Engineering Science and Technology, An International Journal, Vol. 56, 101779, 2024.

17. Hossain, Amran, Rafiqul Islam, Mohammad Tariqul Islam, Phumin Kirawanich, and Mohamed S. Soliman, "FT-FEDTL: A fine-tuned feature-extracted deep transfer learning model for multi-class microwave-based brain tumor classification," Computers in Biology and Medicine, Vol. 183, 109316, 2024.

18. Gupta, Hemant, Vikas Maheshwari, and Vandana Vikas Thakery, "Brain tumor detection by microwave imaging using planner antenna," International Journal of Bio-Science and Bio-Technology, Vol. 8, No. 5, 201-210, 2016.

19. Chandra, Rohit and Ilangko Balasingham, "Detection of brain tumor and localization of a deep brain RF-source using microwave imaging," 2015 9th European Conference on Antennas and Propagation (EuCAP), 1-5, 2015.

20. Asok, Athul O., R. Anjaly, Nissan Kunju, and Sukomal Dey, "Microwave medical imaging using a compact monopole antenna for brain tumor detection," 2023 First International Conference on Microwave, Antenna and Communication (MAC), 1-4, IEEE, 2023.

21. Särestöniemi, Mariella, Daljeet Singh, Rakshita Dessai, Charline Heredia, Sami Myllymäki, and Teemu Myllylä, "Realistic 3D phantoms for validation of microwave sensing in health monitoring applications," Sensors, Vol. 24, No. 6, 1975, 2024.

22. Groumpas, Evangelos, Maria Koutsoupidou, Irene S. Karanasiou, Charalabos Papageorgiou, and Nikolaos Uzunoglu, "Real-time passive brain monitoring system using near-field microwave radiometry," IEEE Transactions on Biomedical Engineering, Vol. 67, No. 1, 158-165, 2019.

23. Hossain, Amran, Mohammad Tariqul Islam, Sharul Kamal Abdul Rahim, Md. Atiqur Rahman, Tawsifur Rahman, Haslina Arshad, Amit Khandakar, Mohamed Arslane Ayari, and Muhammad E. H. Chowdhury, "A lightweight deep learning based microwave brain image network model for brain tumor classification using reconstructed microwave brain (RMB) images ," Biosensors, Vol. 13, No. 2, 238, 2023.

24. Inum, Reefat, Md. Masud Rana, Kamrun Nahar Shushama, and Md. Anwarul Quader, "EBG based microstrip patch antenna for brain tumor detection via scattering parameters in microwave imaging system," International Journal of Biomedical Imaging, Vol. 2018, No. 1, 8241438, 2018.

25. Gupta, Hemant Kumar, Raghavendra Sharma, and Vandana Vikas Thakre, "Tumor detection in multilayer brain phantom model by symmetrical-shaped DGS rectangular microstrip patch antenna," International Conference on Intelligent Computing and Smart Communication 2019: Proceedings of ICSC 2019, 705-712, 2020.

26. Shokry, M. A. and A. M. M. A. Allam, "UWB antenna for brain stroke and brain tumour detection," 2016 21st International Conference on Microwave, Radar and Wireless Communications (MIKON), 1-3, IEEE, 2016.

27. Raihan, Rafat, Mohammad Shams Alam Bhuiyan, Raja Rashidul Hasan, Tulsi Chowdhury, and Rehnuma Farhin, "A wearable microstrip patch antenna for detecting brain cancer," 2017 IEEE 2nd International Conference on Signal and Image Processing (ICSIP), 432-436, IEEE, 2017.

28. Saleeb, Demyana A., Rehab M. Helmy, Nihal F. F. Areed, Mohamed Marey, Wazie M. Abdulkawi, and Ahmed S. Elkorany, "A technique for the early detection of brain cancer using circularly polarized reconfigurable antenna array," IEEE Access, Vol. 9, 133786-133794, 2021.

29. Nair, Vineeta V., Elizabeth George, and Alex James, "Real-time tumor detection using electromagnetic signals with memristive echo state networks," IEEE Internet of Things Journal, Vol. 11, No. 20, 33712-33721, 2024.

30. Sharma, Madan Kumar, Mithilesh Kumar, J. P. Saini, Deepak Gangwar, Binod K. Kanaujia, Satya P. Singh, and Aime’Lay Ekuakille, "Experimental investigation of the breast phantom for tumor detection using ultra-wide band-MIMO antenna sensor (UMAS) probe," IEEE Sensors Journal, Vol. 20, No. 12, 6745-6752, 2020.

31. Saleeb, Demyana A., Rehab M. Helmy, Nihal F. F. Areed, Mohamed Marey, Khaled Mohamad Almustafa, and Ahmed S. Elkorany, "Detection of kidney cancer using circularly polarized patch antenna array," IEEE Access, Vol. 10, 78102-78113, 2022.

32. Al-Gburi, Ahmed Jamall Abdullah, Imran Ibrahim, and Zahriladha Zakaria, "A miniature raspberry shaped UWB monopole antenna based on microwave imaging scanning technique for kidney stone early detection," Int. J. Psychosoc. Rehabil, Vol. 24, No. 2, 1755-1763, 2020.

Mr. Sanjeev Sharma

Dr. Daljeet Singh

Dr. Mariella Särestöniemi

Dr. Teemu Myllylä

Dr. Rajeev Kumar