volume | PIER Journals

Abstract

This paper presents a miniaturized implantable antenna with multi-resonances operating at the Medical Implant Communication Service (MICS) band (402-405) and Industrial, and Medical (ISM) band (433.1-434.8 MHz, 868-868.6 MHz, and 902-928 MHz) for advanced biomedical applications. The proposed antenna is notably compact, occupying a volume of 10 × 10 × 1.27 mm³ (equivalent to 127 mm³). Multi-resonance frequencies are generated by incorporating a shorting pin and a meandered resonator structure. The proposed antenna exhibited wideband characteristics, with bandwidth ratios of 39.5% and 28.8% at 402 and 915 MHz, respectively. Moreover, the performance of the implantable antenna was further validated in different organs within a realistic human body model, such as the heart, stomach, small intestine and colon. The practical performance of the fabricated antenna prototype was validated using a tissue-equivalent liquid phantom. Additionally, to evaluate the transmission performance under real-world scenarios, an on-body antenna matched with the implanted antenna was designed for an in-body to on-body transmission setup. Under the maximum safe input power of 25 μW, link budget analysis demonstrates that data can be transmitted at a rate of 10 Mbps over distances of 9.5 and 12 cm in the MICS and ISM bands, respectively. The simulated and experimental results verified the feasibility of substituting a realistic human model with a homogeneous muscle model in the design of an implantable antenna system and demonstrated a strong potential for diverse implantation scenarios and future biotelemetry applications.

1. Shah, Izaz Ali, Muhammad Zada, and Hyoungsuk Yoo, "Design and analysis of a compact-sized multiband spiral-shaped implantable antenna for scalp implantable and leadless pacemaker systems," IEEE Transactions on Antennas and Propagation, Vol. 67, No. 6, 4230-4234, Jun. 2019.
doi:10.1109/tap.2019.2908252 Google Scholar

2. Cui, Wenjie, Ruipeng Liu, Lu Wang, Mengjun Wang, Hongxing Zheng, and Erping Li, "Design of wideband implantable antenna for wireless capsule endoscope system," IEEE Antennas and Wireless Propagation Letters, Vol. 18, No. 12, 2706-2710, Dec. 2019.
doi:10.1109/lawp.2019.2949630 Google Scholar

3. Xu, Li-Jie, Yong-Xin Guo, and Wen Wu, "Miniaturized dual-band antenna for implantable wireless communications," IEEE Antennas and Wireless Propagation Letters, Vol. 13, 1160-1163, 2014.
doi:10.1109/lawp.2014.2329937 Google Scholar

4. Nikolayev, Denys, Maxim Zhadobov, Laurent Le Coq, Pavel Karban, and Ronan Sauleau, "Robust ultraminiature capsule antenna for ingestible and implantable applications," IEEE Transactions on Antennas and Propagation, Vol. 65, No. 11, 6107-6119, Nov. 2017.
doi:10.1109/tap.2017.2755764 Google Scholar

5. Liu, Changrong, Yong-Xin Guo, and Shaoqiu Xiao, "Circularly polarized helical antenna for ISM-band ingestible capsule endoscope systems," IEEE Transactions on Antennas and Propagation, Vol. 62, No. 12, 6027-6039, Dec. 2014.
doi:10.1109/tap.2014.2364074 Google Scholar

6. Karacolak, Tutku, Robert Cooper, Ercan Selçuk Unlu, and Erdem Topsakal, "Dielectric properties of porcine skin tissue and in vivo testing of implantable antennas using pigs as model animals," IEEE Antennas and Wireless Propagation Letters, Vol. 11, 1686-1689, 2012.
doi:10.1109/LAWP.2013.2241722 Google Scholar

7. Liu, Changrong, Yong-Xin Guo, and Shaoqiu Xiao, "Compact dual-band antenna for implantable devices," IEEE Antennas and Wireless Propagation Letters, Vol. 11, 1508-1511, 2012.
doi:10.1109/lawp.2012.2233705 Google Scholar

8. Xu, Li-Jie, Yong-Xin Guo, and Wen Wu, "Bandwidth enhancement of an implantable antenna," IEEE Antennas and Wireless Propagation Letters, Vol. 14, 1510-1513, 2015.
doi:10.1109/lawp.2014.2374217 Google Scholar

9. Kim, Jaehoon and Y. Rahmat-Samii, "Implanted antennas inside a human body: Simulations, designs, and characterizations," IEEE Transactions on Microwave Theory and Techniques, Vol. 52, No. 8, 1934-1943, Aug. 2004.
doi:10.1109/tmtt.2004.832018 Google Scholar

10. Zada, Muhammad and Hyoungsuk Yoo, "A miniaturized triple-band implantable antenna system for bio-telemetry applications," IEEE Transactions on Antennas and Propagation, Vol. 66, No. 12, 7378-7382, Dec. 2018.
doi:10.1109/tap.2018.2874681 Google Scholar

11. Bakogianni, Sofia and Stavros Koulouridis, "A dual-band implantable rectenna for wireless data and power support at sub-GHz region," IEEE Transactions on Antennas and Propagation, Vol. 67, No. 11, 6800-6810, Nov. 2019.
doi:10.1109/tap.2019.2927879 Google Scholar

12. Shah, Syed Ahson Ali and Hyoungsuk Yoo, "Radiative near-field wireless power transfer to scalp-implantable biotelemetric device," IEEE Transactions on Microwave Theory and Techniques, Vol. 68, No. 7, 2944-2953, Jul. 2020.
doi:10.1109/tmtt.2020.2985356 Google Scholar

13. Faisal, Farooq, Muhammad Zada, Asma Ejaz, Yasar Amin, Sadiq Ullah, and Hyoungsuk Yoo, "A miniaturized dual-band implantable antenna system for medical applications," IEEE Transactions on Antennas and Propagation, Vol. 68, No. 2, 1161-1165, Feb. 2020.
doi:10.1109/tap.2019.2938591 Google Scholar

14. Hayat, Shahzeb, Syed Ahson Ali Shah, and Hyoungsuk Yoo, "Miniaturized dual-band circularly polarized implantable antenna for capsule endoscopic system," IEEE Transactions on Antennas and Propagation, Vol. 69, No. 4, 1885-1895, Apr. 2021.
doi:10.1109/tap.2020.3026881 Google Scholar

15. Li, Rongqiang, Yong-Xin Guo, and Guohong Du, "A conformal circularly polarized antenna for wireless capsule endoscope systems," IEEE Transactions on Antennas and Propagation, Vol. 66, No. 4, 2119-2124, Apr. 2018.
doi:10.1109/tap.2018.2804674 Google Scholar

16. Sharma, Deepti, Vikrant Kaim, Binod Kumar Kanaujia, Neeta Singh, Sachin Kumar, and Karumudi Rambabu, "A triple band circularly polarized antenna for leadless cardiac transcatheter pacing system," IEEE Transactions on Antennas and Propagation, Vol. 70, No. 6, 4287-4298, Jun. 2022.
doi:10.1109/tap.2022.3145461 Google Scholar

17. Faisal, Farooq, Muhammad Zada, Hyoungsuk Yoo, Ismail Ben Mabrouk, Mohamed Chaker, and Tarek Djerafi, "An ultra-miniaturized antenna with ultra-wide bandwidth for future cardiac leadless pacemaker," IEEE Transactions on Antennas and Propagation, Vol. 70, No. 7, 5923-5928, Jul. 2022.
doi:10.1109/tap.2022.3161513 Google Scholar

18. Liu, Changrong, Yong-Xin Guo, and Shaoqiu Xiao, "A hybrid patch/slot implantable antenna for biotelemetry devices," IEEE Antennas and Wireless Propagation Letters, Vol. 11, 1646-1649, 2012.
doi:10.1109/lawp.2013.2237879 Google Scholar

19. Xu, Li-Jie, Yong-Xin Guo, and Wen Wu, "Miniaturized circularly polarized loop antenna for biomedical applications," IEEE Transactions on Antennas and Propagation, Vol. 63, No. 3, 922-930, Mar. 2015.
doi:10.1109/tap.2014.2387420 Google Scholar

20. Kiourti, Asimina and Konstantina S. Nikita, "Miniature scalp-implantable antennas for telemetry in the MICS and ISM bands: Design, safety considerations and link budget analysis," IEEE Transactions on Antennas and Propagation, Vol. 60, No. 8, 3568-3575, Aug. 2012.
doi:10.1109/tap.2012.2201078 Google Scholar

21. Gani, Imran and Hyoungsuk Yoo, "Multi-band antenna system for skin implant," IEEE Microwave and Wireless Components Letters, Vol. 26, No. 4, 294-296, Apr. 2016.
doi:10.1109/lmwc.2016.2538470 Google Scholar

22. Zhang, Ke, Changrong Liu, Xueguan Liu, Huiping Guo, and Xinmi Yang, "Miniaturized circularly polarized implantable antenna for ISM-band biomedical devices," International Journal of Antennas and Propagation, Vol. 2017, No. 1, 9750257, Mar. 2017.
doi:10.1155/2017/9750257 Google Scholar

23. Ganeshwaran, Nithyanandham, Jegadishkumar Kailairajan Jeyaprakash, Mohammed Gulam Nabi Alsath, and Vidhyashree Sathyanarayanan, "Design of a dual-band circular implantable antenna for biomedical applications," IEEE Antennas and Wireless Propagation Letters, Vol. 19, No. 1, 119-123, Jan. 2020.
doi:10.1109/lawp.2019.2955140 Google Scholar

24. Zhang, Xuefang, Long Li, Xuanming Zhang, Qi Zhao, and Yuxiao Lu, "A dual band implantable antenna," 2018 International Applied Computational Electromagnetics Society Symposium --- China (ACES), 1-2, Beijing, China, 2018.
doi:10.23919/ACESS.2018.8669253

25. Kam, Kevin A., Vikrant Kumar, Casey K. Lardner, Isabelle Mollicone, Dani Dumitriu, and Ioannis Kymissis, "A fully integrable 915MHz implantable antenna system for long-range telemetry in rodents," 2023 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), 55-57, Leuven, Belgium, 2023.
doi:10.1109/IMBioC56839.2023.10305092

26. Bahrouni, Majdi, Gregory Houzet, Hichem Trabelsi, and Tan Phu Vuong, "A low profile dual band implantable antenna for biomedical applications," 2023 22nd Mediterranean Microwave Symposium (MMS), 1-4, Sousse, Tunisia, 2023.
doi:10.1109/MMS59938.2023.10421395

27. Nagaoka, Tomoaki, Soichi Watanabe, Kiyoko Sakurai, Etsuo Kunieda, Satoshi Watanabe, Masao Taki, and Yukio Yamanaka, "Development of realistic high-resolution whole-body voxel models of japanese adult males and females of average height and weight, and application of models to radio-frequency electromagnetic-field dosimetry," Physics in Medicine & Biology, Vol. 49, No. 1, 1-15, Dec. 2003.
doi:10.1088/0031-9155/49/1/001 Google Scholar

28. Yilmaz, Tuba, Tutku Karacolak, and Erdem Topsakal, "Characterization of muscle and fat mimicking gels at MICS and ISM bands (402-405 MHz and 2.40-2.48 GHz)," XXIX General Assembly of International Union of Radio Science (URSI), Chicago, Illinois, USA, Aug. 2008.

29. IEEE standard for safety levels with respect to human exposure to radio frequency electromagnetic fields, 3 kHz to 300 GHz, IEEE Std C95.1-2005 (Revision of IEEE Std C95.1-1991), 1-238, Apr. 2006.

30. Cheng, Xiaoyu, David E. Senior, Cheolbok Kim, and Yong-Kyu Yoon, "A compact omnidirectional self-packaged patch antenna with complementary split-ring resonator loading for wireless endoscope applications," IEEE Antennas and Wireless Propagation Letters, Vol. 10, 1532-1535, 2011.
doi:10.1109/lawp.2011.2181315 Google Scholar

31. Wang, J. and Q. Wang, Body Area Communications, Wiley, New York, NY, USA, 2013.

32. Shi, Jingjing, Hailian Liu, Xin Wang, Jiayu Zhang, Fuye Han, Xiaowei Tang, and Jianqing Wang, "Miniaturized dual-resonant helix/spiral antenna system at MHz-band for FSK impulse radio intrabody communications," IEEE Transactions on Antennas and Propagation, Vol. 68, No. 9, 6566-6579, Sep. 2020.
doi:10.1109/tap.2020.2993149 Google Scholar

33. Huang, Jialong, Xiongying Liu, Yi Fan, and Zhenglin Ju, "Dual-band and left-/right-handed circularly polarized implantable antenna for arteriovenous grafts in hemodialysis," IEEE Transactions on Antennas and Propagation, Vol. 73, No. 10, 7207-7220, 2025.
doi:10.1109/tap.2025.3575257 Google Scholar

Dr. Hanwen Miao

Dr. Mengxing Liu

Dr. Le Song

Dr. Jingjing Shi

Dr. Lijia Liu

Dr. Jianqing Wang