volume | PIER Journals

Abstract

This paper presents a diagnosis method for articular cartilage damage using polarization-sensitive optical coherence tomography (PS-OCT). Through signal analysis, the optical characteristics of intact cartilage and different types of mild lesions within cartilages can be quantified from measures such as the scattering coefficient (μ_s), effective anisotropy factor (g_eff), and birefringence coefficient (Δn). Our preliminary investigation using porcine articular cartilage indicated that both subsurface morphological changes and apparent variations in optical properties, which may be the early signs of cartilage degeneration, were found in three types of diseased cartilages.

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Dr. Jeou-Jong Shyu

Dr. Che-Hung Chan

Dr. Ming-Wei Hsiung

Dr. Po-Nien Yang

Dr. Huei-Wen Chen

Prof. Wen-Chuan Kuo