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2009-07-15
A Reverberation Chamber to Investigate the Possible Effects of "in Vivo" Exposure of Rats to 1.8 GHz Electromagnetic Fields: a Preliminary Study
By
Progress In Electromagnetics Research, Vol. 94, 133-152, 2009
Abstract
A system generating 1.8 GHz electromagnetic fields for bio-medical and behavioral study on laboratory animals was designed and implemented. The system is based on a reverberation chamber. An input power up to 5 W can be sent to an indoor transmitting antenna and an electric field strength (E) more than 90 V/m can be reached inside the chamber. The system was characterized at different input powers measuring E in different points by means of a miniature sensor. Then, boxes with 300 cc of physiological liquid inside were realized as simple phantoms simulating laboratory animals (rats) and E inside the liquid was measured, performing several simulations by moving the phantoms (1,2) in the chamber and/or putting them still in different positions. On the basis of these measurements, the SAR (Specific Absorption Rate) and the Pe (power efficiency = SAR/input power) were determined at different powers. The actual system is characterized by a low power efficiency with respect to the "in vivo" exposition systems based on transversal electromagnetic (TEM) cells. Its advantage is to have inside the chamber a habitat similar to the usual one for the laboratory animals.
Citation
Pier Francesco Biagi L. Castellana Tommaso Maggipinto G. Maggipinto Teresa Ligonzo Luigi Schiavulli Domenico Loiacono Anita Ermini Maria Lasalvia Giuseppe Perna Vito Capozzi , "A Reverberation Chamber to Investigate the Possible Effects of "in Vivo" Exposure of Rats to 1.8 GHz Electromagnetic Fields: a Preliminary Study," Progress In Electromagnetics Research, Vol. 94, 133-152, 2009.
doi:10.2528/PIER09061006
http://www.jpier.org/PIER/pier.php?paper=09061006
References

1. Adey, W. R., et al., "Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836MHz modulated microwaves," Radiat. Res., Vol. 152, 293-302, 1999.
doi:10.2307/3580329

2. Adey, W. R., et al., "Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats exposed to frequency-modulated microwave fields," Cancer Res., Vol. 60, 1857-1863, 2000.

3. Frei, M. R., et al., "Chronic exposure of cancer-prone mice to low level 2450 MHz radiofrequency radiation," Bioelectromag., Vol. 19, 20-31, 1998.
doi:10.1002/(SICI)1521-186X(1998)19:1<20::AID-BEM2>3.0.CO;2-6

4. Gatta, L., R. Pinto, V. Ubaldi, L. Pace, P. Galloni, G. A. Lovisolo, C. Marino, and C. Pioli, "Effects of in vivo exposure to GSM-modulated 900MHz on mouse peripheral hymphocytes," Radiat. Res., Vol. 160, 600-605, 2003.
doi:10.1667/RR3078

5. Wu, B. I., F. C. A. I. Cox, and J. A. Kong, "Experimental methodology for non-thermal effects of electromagnetic radiation on biologics," Journal of Electromagnetic Waves and Applications, Vol. 21, No. 4, 533-548, 2007.
doi:10.1163/156939307780616829

6. Lopez-Martin, E., J. C. Bregains, F. J. Jorge-Barreiro, J. L. Sebastián-Franco, E. Moreno-Piquero, and F. J. Ares-Pena, "An experimental set-up for measurement of the power absorbed from 900MHz GSM standing waves by small animals," Progress In Electromagnetics Research, Vol. 87, 149-165, 2008.
doi:10.2528/PIER08101307

7. Heikkinen, P., V. M. Kosma, T. Hongisto, H. Huuskonen, P. Hyysalo, H. Komulainen, T. Kumlin, J. T. Laitinen, S. Lang, L. Puranen, and J. Juutil, "Effects of mobile phone radiation on x-ray-induced tumorigenesis in mice," Radiat. Res., Vol. 156, 775-785, 2001.
doi:10.1667/0033-7587(2001)156[0775:EOMPRO]2.0.CO;2

8. Heikkinen, P., V. M. Kosma, L. Alhonen, H. Huuskonen, H. Komulainen, T. Kumlin, J. T. Laitinen, S. Lang, L. Puranen, and J. Juutilainen, "Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice," Int. J. Radiat. Biol., Vol. 79, 221-233, 2003.
doi:10.1080/0955300031000096298

9. Imaida, K., M. Taki, T. Yamaguchi, T. Ito, S.Watanabe, K.Wake, A. Aimoto, Y. Kamimura, and T. Shirai, "Lack of promoting e®ects of the electromagnetic near-field used for cellular phones (929 MHz) on rat liver carcinogenesis in medium-term bioassay," Carcinogenesis, Vol. 19, 311-314, 1998.
doi:10.1093/carcin/19.2.311

10. Imaida, K., M. Taki, S. Watanabe, Y. Kamimura, T. Ito, and T. Shirai, "The 1.5 GHz electromagnetic near-field used for cellular phones does not promote rat liver carcinogenesis in a medium term liver bioassay," Japan J. Cancer Res., Vol. 89, 995-1002, 1998.

11. Malyapa, R. S., et al., "DNA damage in rat brain cells after in vivo exposure to 2450MHz electromagnetic radiation and various methods of euthanasia," Radiat. Res., Vol. 149, 637-645, 1998.
doi:10.2307/3579911

12. Toler, J. C., et al., "Long-term low-level exposure of mice prone tomammary tumors to 435MHz radiofrequency radiation," Radiat. Res., Vol. 148, 227-234, 1997.
doi:10.2307/3579606

13 . Verschaeve, L. and A. Maes, "Genetic, carcinogenic and teratogenic effects of radiofrequency fields," Mutation Research, Vol. 410, 141-165, 1998.

14. Corona, P., G. Ferrara, and M. Migliaccio, "Reverberating chambers as sources of stochastic electromagnetic fields," IEEE Transactions on Electromagnetic Compatibility, Vol. 38, 3, 1996.

15. Hill, D. A, "Electromagnetic theory of reverberation chambers,", NIST Technical Note 1506, National Institute of Standards and Technology, Boulder, Colorado 80303-3328, USA, 1998.

16. Kouveliotis, N. K., P. T. Trakadas, and C. N. Capsalis, "FDTD modeling of a vibrating intrinsic reverberation chamber," Progress In Electromagnetics Research, Vol. 39, 47-59, 2003.
doi:10.2528/PIER02050804

17. Crawford, L. and G. H. Koepke, "Design, evaluation and use of a reverberation chamber for performing electromagnetic susceptibility/vulnerability measurements," National Bureau of Standard (NBS), 1092, 1986.

18., , IEEE C95.3-2002, IEEE Recommended Practice for Measurements and Computations of Radio Frequency Electromagnetic Fields with Respect to Human Exposure to Such Fields, 100 kHz--300 GHz, The Institute of Electrical and Electronic Engineers, Inc., New York, NY, 10016--5997, 2002.

19. Andreuccetti, D., M. G. Bini, A. Ignesti, R. Olmi, N. Rubino, and R. Vanni, "Use of polyacrylamide as a tissue-equivalent material in the microwave range," IEE Trans. Microw. Theory Tech., Vol. 35, 275-277, 1988.

20. Chou, C.-K., G.-W. Chen, A. Guy, and K. H. Luk, "Formulas for preparing phantom muscle tissue at various radiofrequencies," Bioelectromag., Vol. 5, 435-441, 1984.
doi:10.1002/bem.2250050408

21. Lazebnik, M., E. L. Madsen, G. R. Frank, and S. C. Hagness, "Tissue-mimicking phantom materials for narrowband and ultrawideband microwave applications," Phys. Med. Biol., Vol. 50, 4245-4258, 2005.
doi:10.1088/0031-9155/50/18/001

22. McCann, C., J. C. Kumaradas, M. R. Gertner, S. R. H. Davidson, A. M. Dolan, and M. D. Sherar, "Feasibility of salvage interstitial microwave thermal therapy for prostate carcinoma following failed brachytherapy: Study in a tissue equivalent phantom," Phys. Med. Biol., Vol. 48, 1041-1052, 2003.
doi:10.1088/0031-9155/48/8/306

23. Ardoino, L., V. Lopresto, S. Mancini, C. Marino, R. Pinto, and G. A. Lovisolo, "A radio-frequency system for in vivo pilot experiments aimed at the studies on biological effects of electromagnetic fields," Phys. Med. Biol., Vol. 50, 3643-3654, 2005.
doi:10.1088/0031-9155/50/15/011