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2010-04-15
Channel-Ranked Beamformer for the Early Detection of Breast Cancer
By
Progress In Electromagnetics Research, Vol. 103, 153-168, 2010
Abstract
Confocal Microwave Imaging (CMI) for the early detection of breast cancer is based on several assumptions regarding the dielectric properties of normal and malignant breast tissue. One of these assumptions is that the breast is primarily dielectrically homogeneous, and that the propagation, attenuation and phase characteristics of normal breast tissue allows for the constructive addition of the UWB returns from dielectric scatterers within the breast. However, recent studies by Lazebnik et al. have highlighted a very signicant dielectric contrast between normal adipose and broglandular tissue within the breast. This dielectric heterogeneity presents a considerably more challenging imaging scenario, where constructive addition of the UWB returns, and therefore tumor detection, is much more dicult. In a dielectrically homogeneous breast, each additional beamformed backscattered signal adds coherently with existing signals, resulting in an improved image of any dielectric scatterers present. However, in a dielectrically heterogeneous breast, signals with a longer propagation distance are more likely to encounter heterogeneity and therefore are more prone to incoherent addition, reducing the overall quality of the breast image. In this paper, a novel beamforming algorithm is described, which gives extra weighting to signals with shorter propagation distances to create an improved image of the breast. The beamformer is shown to provide improved images of more dielectrically heterogeneous breasts than the traditional delay and sum beamformer from which it is derived.
Citation
Martin O'Halloran Martin Glavin Edward Jones , "Channel-Ranked Beamformer for the Early Detection of Breast Cancer," Progress In Electromagnetics Research, Vol. 103, 153-168, 2010.
doi:10.2528/PIER10030902
http://www.jpier.org/PIER/pier.php?paper=10030902
References

1. Nass, S. L., I. C. Henderson, and J. C. Lashof, Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer, National Academy Press, 2001.

2. Wang, L., X. Zhao, H. Sun, and G. Ku, "Microwave-induced acoustic imaging of biological tissues," Rev. Sci. Instrum., Vol. 70, No. 9, 3744-3748, 1991.
doi:10.1063/1.1149986

3. Li, D., P. M. Meaney, T. Raynolds, S. A. Pendergrass, M. W. Fanning, and K. D. Paulsen, "Parallel-detection microwave spectroscopy system for breast cancer imaging," Rev. Sci. Instrum., Vol. 75, No. 7, 2305-2313, 2004.
doi:10.1063/1.1764609

4. Kruger, R. A., K. D. Miller, H. E. Reynolds, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, "Breast cancer in vivo: Contrast enhancement with thermoacoustic CT at 434MHz --- Feasibility study," Radiology, Vol. 216, No. 1, 279-283, 2000.

5. Bulyshev, A., S. Y. Semenov, A. E. Souvorov, R. H. Svenson, A. G. Nazorov, Y. E. Sizov, and G. P. Tatsis, "Computational modeling of three-dimensional microwave tomography of breast cancer," IEEE Trans. Biomed. Eng., Vol. 48, No. 9, 1053-1056, Sep. 2001.
doi:10.1109/10.942596

6. Meaney, P. M., M. W. Fanning, D. Li, S. P. Poplack, and K. D. Paulsen, "A clinical prototype for active microwave imaging of the breast," IEEE Trans. Microwave Theory Tech., Vol. 48, No. 11, 1841-1853, Nov. 2000.

7. Meaney, P. M., K. D. Paulsen, J. T. Chang, M. W. Fanning, and A. Hartov, "Nonactive antenna compensation for fixed-array microwave imaging: Part II --- Imaging results," IEEE Trans. Med. Imag., Vol. 18, No. 6, 508-518, Jun. 1999.
doi:10.1109/42.781016

8. Souvorov, A. E., A. E. Bulyshev, S. Y. Semenov, R. H. Svenson, and G. P. Tatis, "Two-dimensional analysis of a microwave flat antenna array for breast cancer tomography," IEEE Trans. Microwave Theory Tech., Vol. 48, No. 8, 1413-1415, Aug. 2000.
doi:10.1109/22.859490

9. Bulyshev, A. E., S. Y. Semenov, A. E. Souvorov, R. H. Svenson, A. G. Nazorov, Y. E. Sizov, and G. P. Tatsis, "Computational modeling of three-dimensional microwave tomography of breast cancer," IEEE Trans. Biomed. Eng., Vol. 48, No. 9, 1053-1056, Sep. 2001.
doi:10.1109/10.942596

10. Liu, Q. H., Z. Q. Zhang, T. Wang, J. A. Byran, G. A. Ybarra, L. W. Nolte, and W. T. Joines, "Active microwave imaging i --- 2-d forward and inverse scattering methods," IEEE Trans. Microwave Theory Tech., Vol. 50, No. 1, 123-133, Jan. 2002.
doi:10.1109/22.981256

11. Hagness, S. C., A. Taflove, and J. E. Bridges, "Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors ," IEEE Trans. Biomed. Eng., Vol. 45, No. 12, 1470-1479, 1998.
doi:10.1109/10.730440

12. Hagness, S. C., "Three-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Design of an antennaarray element ," IEEE Trans. Antennas and Propagat., Vol. 47, No. 5, 783-791, May 1999.
doi:10.1109/8.774131

13. Fear, E. C., X. Li, S. C. Hagness, and M. A. Stuchly, "Confocal microwave imaging for breast cancer detection: Localization of tumors in three dimensions," IEEE Trans. Biomed. Eng., Vol. 49, No. 8, 812-822, Aug. 2002.
doi:10.1109/TBME.2002.800759

14. Fear, E. C. and M. A. Stuchly, "Microwave system for breast tumor detection," IEEE Microwave and Guided Wave Letters, Vol. 9, No. 11, 470-472, Nov. 1999.
doi:10.1109/75.808040

15. Fear, E. C., J. Sill, and M. A. Stuchly, "Experimental feasibility study of confocal microwave imaging for breast tumor detection," IEEE Trans. Microwave Theory Tech., Vol. 51, No. 3, 887-892, Mar. 2003.
doi:10.1109/TMTT.2003.808630

16. Fear, E., J. Sill, and M. Stuchly, "Microwave system for breast tumor detection: Experimental concept evaluation," IEEE AP-S International Symposium and USNC/URSI Radio Science Meeting, Vol. 1, 819-822, San Antonio, Texas, Jun. 2002.

17. Li, X. and S. C. Hagness, "A confocal microwave imaging algorithm for breast cancer detection," IEEE Microwave and Wireless Components Letters, Vol. 11, No. 3, 130-132, 2001.
doi:10.1109/7260.915627

18. Li, X., E. J. Bond, B. D. V. Veen, and S. C. Hagness, "An overview of ultra-wideband microwave imaging via space-time beamforming for early-stage breast-cancer detection ," IEEE Antennas and Propagation Magazine, Vol. 47, No. 1, 19-34, Feb. 2005.
doi:10.1109/MAP.2005.1436217

19. Craddock, I. J., R. Nilavalan, J. Leendertz, A. Preece, and R. Benjamin, Experimental investigation of real aperture synthetically organised radar for breast cancer detection, IEEE AP-S International Symposium, Washington, DC, 2005.

20. Hernandez-Lopez, M., M. Quintillan-Gonzalez, S. Garcia, A. Bretones, and R. Martin, "A rotating array of antennas for confocal microwave breast imaging," Microw. Opt. Technol. Lett., Vol. 39, No. 4, 307-311, Nov. 2000.
doi:10.1002/mop.11199

21. De Rodriguez, M., M. Vera-Isasa, and V. S. del Rio, "3-D microwave breast tumor detection: Study of system performance," IEEE Trans. Biomed. Eng., Vol. 55, No. 12, 2772-2777, 2008.
doi:10.1109/TBME.2008.2003082

22. Lazebnik, M., L. McCartney, D. Popovic, C. B. Watkins, M. J. Lindstrom, J. Harter, S. Sewall, A. Magliocco, J. H. Booske, M. Okoniewski, and S. C. Hagness, "A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries," Phys. Med. Biol., Vol. 52, 2637-2656, 2007.
doi:10.1088/0031-9155/52/10/001

23. Lazebnik, M., D. Popovic, L. McCartney, C. B. Watkins, M. J. Lindstrom, J. Harter, S. Sewall, T. Ogilvie, A. Magliocco, T. M. Breslin, W. Temp, D. Mew, J. H. Booske, M. Okoniewski, and S. C. Hagness, "A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries," Phys. Med. Biol., Vol. 52, 6093-6115, 2007.
doi:10.1088/0031-9155/52/20/002

24. O'Halloran, M., M. Glavin, and E. Jones, "Effects of fibroglandular tissue distribution on data-independent beamformering algorighms," Progress In Electromagnetic Research, Vol. 97, 141-158, 2009.
doi:10.2528/PIER09081701

25. O'Halloran, M., R. Conceicao, D. Byrne, M. Glavin, and E. Jones, "FDTD modeling of the breast: A review," Progress In Electromagnetics Research B, Vol. 18, 1-24, 2009.
doi:10.2528/PIERB09080505

26. Chaudhary, S. S., R. K. Mishra, A. Swarup, and J. M. Thomas, "Dielectric properties of normal and malignant human breast tissue at radiowave and microwave frequencies ," Indian J. Biochem. Biophys., Vol. 21, 76-79, 1984.

27. Surowiec, A. J., S. S. Stuchly, J. R. Barr, and A. Swarup, "Dielectric properties of breast carcinoma and the surrounding tissues ," IEEE Trans. Biomed. Eng., Vol. 35, No. 4, 257-263, Apr. 1988.
doi:10.1109/10.1374

28. Joines, W. T., Y. Zhang, C. Li, and R. L. Jirtle, "The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz," Med. Phys., Vol. 21, No. 4, 547-550, Apr. 1994.
doi:10.1118/1.597312

29. Campbell, A. M. and D. V. Land, "Dielectric properties of female human breast tissue measured in vitro at 3.2 GHz," Phys. Med. Biol., Vol. 37, No. 1, 193-210, 1992.

31. Haykin, S. and A. Steinhardt, Adaptive Radar Detection and Estimation, John Wiley and Sons, 1992.

32. Fear, E. C. and M. A. Stuchly, "Microwave detection of breast cancer," IEEE Trans. Microwave Theory Tech., Vol. 48, No. 11, 1854-1863, Nov. 2000.

33. Bond, E. J., X. Li, S. C. Hagness, B. D. V. Veen, and , "Microwave imaging via space-time beamforming for early detection of breast cancer ," IEEE Trans. Antennas and Propagat., Vol. 51, No. 8, 1690-1705, Aug. 2003.

34. Gabriel, C., S. Gabriel, and E. Corthout, "The dielectric properties of biological tissues: I. Literature survey," Phys. Med. Biol., Vol. 41, 2231-2249, 1996.

35. Gabriel, S., R. W. Lau, and C. Gabriel, "The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz ," Phys. Med. Biol., Vol. 41, 2251-2269, 1996.

36. Fear, E. C. and M. Okoniewski, "Confocal microwave imaging for breast tumor detection: Application to a hemispherical breast model ," 2002 IEEE MTT-S International Microwave Symposium Digest , Vol. 3, 1759-1762, Seattle, WA, USA, 2002.

37. Klemm, M., I. J. Craddock, J. A. Leendertz, A. Preece, and R. Benjamin, "Improved delay-and-sum beamforming algorithm for breast cancer detection," International Journal of Antennas and Propagation, Vol. 2008, 2008.

38. Conceicao, R. C., M. O'Halloran, M. Glavin, and E. Jones, "Antenna configurations for ultra wide band radar detection of breast cancer," Progress in Biomedical Optics and Imaging, Vol. 7169, San Jose, CA, Jan. 2009.