volume | PIER Journals

The concentration induced permittivity change involves a dispersion which occurs at the resonant frequency, and is often not predictable by simulation using the traditional Cole-Cole model. To overcome this problem, a new Lorentz's model is proposed as a substitute for the Cole-Cole model. Under this new model, the glucose concentration is expected to be measured at the contact interface in the form of a resonant frequency shift. With the help of the model, a contact-based meander-line antenna sensor (CMS) is realized with a high ``sensitivity of 1.3158 dB/(mmol/L) in terms of d |S₁₁|/dC, or of 17~18 MHz/(mmol/L) in terms of'' dω/dC. The model has been experimentally validated with in-vitro measurements and for proof-of-concept with in-vivo clinical investigations in the microwave frequency. Consistent with the predictions of model, a linear ``correlation is observed not only between the resonant frequency shift and the glucose concentration, but also between the S-parameters magnitude and glucose'' concentration.

Dr. Abhishek Kandwal

Dr. Louis W. Y. Liu

Dr. Jingzhen Li

Dr. Yuhang Liu

Dr. Huajie Tang

Dr. Ziheng Ju

Dr. Tobore Igbe

Dr. Rohit Jasrotia

Dr. Zedong Nie